Solved (look at the end for solution, symptoms are at the start).
Still can't get Visilogic 9.7.60 to work in Windows 10. I have tried to clean the registry of all Unitronics entries, clear the directory after uninstalling all Unitronics software. I am getting an "Unhandled exception" "Access to the path 'C:\Program Files (x86)\Unitronics\Remote Operator\Recent Projects.xml' is denied." error when trying to use Remote Operator (install when fine). The folder is present, but the files is not there.
Also still getting the "Load 9Permission denied" error after clean install in Windows 10.