I've seen far too many posts over the years from people who lost days or weeks of work because of a corrupted project file. It happens with the best of software and the most reliable computers. There is one simple trick you can do to minimize your loss - every so often (I do it at least every day), when you've made sufficient changes that reconstructing them would be painful, save your file with a new name (typically just change a rev number). You will now have multiple copies of your file and if the latest file goes bad, you have an available backup.
Further, as you should with every data file you have on your computer, back up to another location (or two!). I back up my data to a thumb drive every time I leave my computer and additionally back up my desktop data to my laptop (and vice-versa) when I use my laptop.
Now ask me if I've ever lost any critical data. The answer will not surprise you.